M. Gil

Single-character insertion-deletion model preserves long indels in ancestral sequence reconstruction

The paper evaluates ARPIP's ability to reconstruct ancestral sequences with long indels, showing it preserves gap length distributions and captures deletion bias in mammalian proteins.

Adipose microenvironment promotes hypersialylation of ovarian cancer cells

This study shows that the adipose microenvironment increases sialylation in ovarian cancer cells, promoting tumor growth in immune-dependent settings.

Ena/VASP proteins at the crossroads of actin nucleation pathways in dendritic cell migration

This study shows that Ena/VASP proteins are essential for dendritic cell migration by coordinating actin nucleation pathways through interactions with formin mDia1 and the WAVE complex.

A TPR scaffold couples signal detection to OdhI phosphorylation in metabolic control by the protein kinase PknG

This study identifies a TPR scaffold in PknG that links signal detection to OdhI phosphorylation, regulating metabolic control in actinobacteria.

Proteome remodeling in the Mycobacterium tuberculosis PknG knockout: molecular evidence for the role of this kinase in cell envelope biogenesis and hypoxia response.

This study uses proteomics to show that PknG knockout in M. tuberculosis alters the proteome, affecting cell envelope biosynthesis and hypoxia response.

Essential Role of Placenta Derived Interferon Stimulated Gene 20 Against ZIKA Virus Infection

This study identifies ISG20 as a key antiviral factor against Zika virus in trophoblast cells and demonstrates the therapeutic potential of recombinant ISG20-Fc protein.

SopB- and SifA-dependent shaping of the Salmonella-containing vacuole proteome in the social amoeba Dictyosteliumdiscoideum

This study identifies SopB and SifA as essential for Salmonella to modify the SCV proteome in Dictyostelium discoideum, enabling intracellular survival.