Author

D. T. Braddock

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

J. D. Humphrey· 2 shared N. Mikush· 2 shared S.-I. Murtada· 2 shared Y. Kawamura· 2 shared A. B. Ramachandra· 1 shared A. Liao· 1 shared A. Maxwell· 1 shared A. W. Caulk· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPathology

J. D. Humphrey

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Lonafarnib improves cardiovascular function and survival in a mouse model of Hutchinson-Gilford Progeria Syndrome

S.-I. Murtada, N. Mikush, M. Wang, P. Ren, Y. Kawamura, A. B. Ramachandra, D. T. Braddock, G. Tellides, L. B. Gordon, J. D. Humphrey

Lonafarnib improves cardiovascular function and survival in a progeria mouse model by reducing pulse wave velocity and enhancing left ventricular diastolic function.

bioRxiv · Dec 17, 2021Pathology

Essential Role of Placenta Derived Interferon Stimulated Gene 20 Against ZIKA Virus Infection

J. Ding, P. Aldo, C. M. Roberts, P. R. Stabach, H. Liu, Y. You, X. Qiu, J. Jeong, A. Maxwell, B. D. Lindenbach, D. T. Braddock, A. Liao, M. Gil

This study identifies ISG20 as a key antiviral factor against Zika virus in trophoblast cells and demonstrates the therapeutic potential of recombinant ISG20-Fc protein.

bioRxiv · Jan 13, 2021Immunology

Paradoxical Aortic Stiffening and Subsequent Cardiac Dysfunction in Hutchinson-Gilford Progeria Syndrome

S.-I. Murtada, Y. Kawamura, A. W. Caulk, H. Ahmadzadeh, N. Mikush, K. Zimmerman, D. Kavanagh, D. Weiss, M. Latorre, Z. W. Zhuang, G. S. Shadel, D. T. Braddock, J. D. Humphrey

This study shows that aortic stiffening and cardiac dysfunction in HGPS mice occur due to loss of smooth muscle function and proteoglycan accumulation, independent of sex, with potential therapeutic implications.

bioRxiv · Oct 2, 2019Bioengineering