Author

M. H. Roehrl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 6 Organism:human· 6 Assay:proteomics· 6 Approach:experimental assay· 5 Research Focus:differential expression· 4 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

J. Y. Wang· 6 shared M. W. Roehrl· 5 shared V. B. Roehrl· 5 shared W. Zhang· 4 shared A. Chow· 1 shared A. Quintanal-Villalonga· 1 shared B. Houck-Loomis· 1 shared C. A. Iacobuzio-Donahue· 1 shared

Activity by Year

2020-2021 · peak 6/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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6 shared papersImmunology

J. Y. Wang

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

A Master Autoantigen-ome Links Alternative Splicing, Female Predilection, and COVID-19 to Autoimmune Diseases

J. Y. Wang, M. W. Roehrl, V. B. Roehrl, M. H. Roehrl

The paper identifies a master autoantigen-ome linking alternative splicing, female predilection, and COVID-19 to autoimmune diseases through analysis of 751 autoantigens across six human cell types.

bioRxiv · Jul 30, 2021Immunology

An Autoantigen Profile from Jurkat T-Lymphoblasts Provides a Molecular Guide for Investigating Autoimmune Sequelae of COVID-19

J. Y. Wang, W. Zhang, M. W. Roehrl, V. B. Roehrl, M. H. Roehrl

This study identifies 140 autoantigens from Jurkat T-cells, showing 75% are autoantibody targets and 89% are altered in SARS-CoV-2 infection, linking them to autoimmune and cancer-related pathways.

bioRxiv · Jul 5, 2021Immunology

An Autoantigen-ome from HS-Sultan B-Lymphoblasts Offers a Molecular Map for Investigating Autoimmune Sequelae of COVID-19

J. Y. Wang, W. Zhang, V. B. Roehrl, M. W. Roehrl, M. H. Roehrl

This study identifies 362 autoantigens from HS-Sultan B-lymphoblasts, showing 87% are affected by SARS-CoV-2 infection, offering insights into COVID-19-induced autoimmunity.

bioRxiv · Apr 5, 2021Immunology

An Autoantigen Profile of Human A549 Lung Cells Reveals Viral and Host Etiologic Molecular Attributes of Autoimmunity in COVID-19

J. Y. Wang, W. Zhang, M. W. Roehrl, V. B. Roehrl, M. H. Roehrl

This study identifies 348 autoantigens from human A549 lung cells, revealing viral and host factors involved in autoimmunity during SARS-CoV-2 infection.

bioRxiv · Feb 21, 2021Immunology

An Autoantigen Atlas from Human Lung HFL1 Cells Offers Clues to Neurological and Diverse Autoimmune Manifestations of COVID-19

J. Y. Wang, W. Zhang, M. W. Roehrl, V. B. Roehrl, M. H. Roehrl

The study identifies an autoantigenome from human lung HFL1 cells using dermatan sulfate affinity, linking it to neurological and autoimmune complications of COVID-19.

bioRxiv · Jan 24, 2021Immunology

Dermatan Sulfate Is a Potential Master Regulator of IgH via Interactions with Pre-BCR, GTF2I, and BiP ER Complex in Pre-B Lymphoblasts

J. Lee, J.-h. Rho, M. H. Roehrl, J. Y. Wang

This study identifies dermatan sulfate (DS) as a master regulator of IgH in pre-B cells by interacting with pre-BCR components, GTF2I, and ER proteins, influencing autoreactive B cell development and autoimmunity.

bioRxiv · Jan 18, 2021Immunology

Multi-omic analysis of lung tumors defines pathways activated in neuroendocrine transformation

A. Quintanal-Villalonga, H. Taniguchi, M. A. Hasan, F. Meng, F. Uddin, M. Donoghue, H. H. Won, S. S. Chavan, J. M. Chan, M. Ciampricotti, A. Chow, M. Offin, J. C. Chang, J. Ray-Kirton, J. Egger, , T. Sen

The paper identifies molecular mechanisms of neuroendocrine transformation in lung cancer using multi-omic analysis of tumors and clinical samples.

bioRxiv · Dec 2, 2020 · PreprintCancer Biology