M. Haber

The polyamine transporter ATP13A3 mediates DFMO-induced polyamine uptake in neuroblastoma

This study identifies ATP13A3 as a polyamine transporter mediating DFMO-induced polyamine uptake in neuroblastoma, highlighting it as a therapeutic target.

Comprehensive multi-platform tyrosine kinase profiling reveals novel actionable FGFR aberrations across pediatric and AYA sarcomas

The paper identifies FGFR aberrations as actionable targets in pediatric and AYA sarcomas using multi-platform profiling and shows FGFR inhibitors can inhibit tumor growth in PDX models.

Ghost admixture in eastern gorillas

The paper identifies archaic admixture in eastern gorillas using whole genome sequences and ABC with neural networks, finding introgression from a ghost lineage into their common ancestor.

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

This study identifies PLK1 as a target of EYA4 and EYA1 phosphatases, showing that dephosphorylation of pY445 promotes PLK1 activation and mitosis, with implications for cancer therapy.

A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer

The paper develops a 15-gene immune signature to identify T-cell infiltration in high-risk paediatric cancers, finding up to 31% of such cancers have infiltrating T-cells.

Understanding the microbial biogeography of ancient human dentitions to guide study design and interpretation

This study examines microbial biogeography in ancient dental calculus to assess sampling biases and environmental contamination.

A freshwater radiation of diplonemids

The paper detects freshwater diplonemids in multiple lakes, finds they form a new lineage, and suggests marine diplonemid diversity may be overestimated.

Particle-associated and free-living bacterial communities in an oligotrophic sea are affected by different environmental and anthropogenic factors

The paper examines how environmental and anthropogenic factors influence particle-associated and free-living bacterial communities in the Eastern Mediterranean Sea, finding distinct dynamics between the two communities.

Microbial communities in an ultra-oligotrophic sea are more affected by season than by distancefrom shore

The paper examines how microbial communities in the ultra-oligotrophic Eastern Mediterranean Sea vary with season and distance from shore, finding that season has a greater impact than distance.