Author

M. Hao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Q. Chen· 2 shared T. Imamichi· 2 shared W. Chang· 2 shared Y. Yang· 2 shared C. Chen· 1 shared C. Wang· 1 shared C. Yu· 1 shared D. Pirottin· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

Q. Chen

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The C-terminal domain of RNase H and the C-terminus amino acid residue regulate virus release and autoprocessing of a defective HIV-1 possessing M50I and V151I changes in integrase

T. Imamichi, C. Chen, M. Hao, W. Chang, Y. Yang

This study identifies the C-terminal domains of RNase H and integrase as regulators of virus release and autoprocessing in a defective HIV-1 variant with specific mutations.

bioRxiv · Oct 23, 2022Microbiology

Enteric glial cells favour accumulation of anti-inflammatory macrophages during the resolution of muscularis inflammation

M. Stakenborg, S. Abdurahiman, V. De Simone, G. Goverse, N. Stakenborg, L. Van Baarle, Q. Wu, D. Pirottin, J.-S. Kim, L. Maor, I. Pintelon, S. Thys, L. Boon, M. Hao, J. Van Ginderachter, , G. Matteoli

This study identifies how enteric glial cells promote the differentiation of anti-inflammatory macrophages during muscularis inflammation resolution through CCL2 and CSF1 signaling.

bioRxiv · Jun 10, 2021Immunology

Natural Occurring Non-Synonymous Single Nucleotide Polymorphisms in Integrase and RNase H Regulate Assembly and Autoprocessing of HIV-1

T. Imamichi, J. G. Bernbaum, S. Laverdure, J. Yang, Q. Chen, H. Highbarger, M. Hao, H. Sui, R. Dewar, W. Chang, H. C. Lane

This paper investigates the impact of 14 non-synonymous SNPs in HIV on viral fitness, finding that specific mutations in integrase and RNase H impair GagPol autoprocessing and replication.

bioRxiv · Mar 15, 2021Microbiology

A potent neutralizing human antibody reveals the N-terminal domain of the Spike protein of SARS-CoV-2 as a site of vulnerability

X. Chi, R. Yan, J. Zhang, G. Zhang, Y. Zhang, M. Hao, Z. Zhang, P. Fan, Y. Dong, Y. Yang, Z. Chen, Y. Guo, J. Zhang, Y. Li, X. Song, , W. Chen

This paper identifies a potent neutralizing antibody targeting the N-terminal domain of SARS-CoV-2 Spike protein, revealing it as a new therapeutic target.

bioRxiv · May 8, 2020Biochemistry

Quantitative Analysis of Interactive Behavior of Mitochondria and Lysosomes Using Structured Illumination Microscopy

Q. Chen, X. Shao, M. Hao, Z. Tian, C. Wang, F. Liu, K. Zhang, F. Wang, P. Ling, J.-L. Guan, J. Diao

The paper introduces an M-value to quantify mitochondria-lysosome contact and mitophagy using structured illumination microscopy, finding distinct M-value ranges for these processes.

bioRxiv · Oct 16, 2018Cell Biology