Author

M. J. Kratochvil

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:database / resource· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

P. L. Bollyky· 3 shared Q. Chen· 3 shared A. Hargil· 2 shared J. D. Pourtois· 2 shared N. L. Haddock· 2 shared S. C. Heilshorn· 2 shared A. E. Barron· 1 shared A. Gupta· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersMicrobiology

P. L. Bollyky

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Author profile →

3 papers

Recent·Most cited

Pf bacteriophages hinder sputum antibiotic diffusion via electrostatic binding

Q. Chen, P. Cai, T. H. W. Chang, E. Burgener, M. J. Kratochvil, A. Gupta, A. Hargil, P. R. Secor, J. E. Nielsen, A. E. Barron, C. Milla, S. C. Heilshorn, A. J. Spakowitz, P. L. Bollyky

This study shows Pf phages and sputum polymers reduce antibiotic diffusion through electrostatic binding and liquid crystal formation in chronic Pseudomonas aeruginosa infections.

bioRxiv · Mar 10, 2024 · PreprintMicrobiology

Rapid assessment of changes in phage bioactivity using dynamic light scattering

T. Dharmaraj, M. J. Kratochvil, J. D. Pourtois, Q. Chen, M. Hajfathalian, A. Hargil, Y.-H. Lin, Z. R. Evans, A. Oromi-Bosch, J. D. Berry, R. McBride, N. L. Haddock, D. R. Holman, J. D. Van Belleghem, T. H. Chang, , P. L. Bollyky

This paper uses Dynamic Light Scattering to assess phage bioactivity changes over time and optimize storage conditions for clinical phage applications.

bioRxiv · Jul 2, 2023Biophysics

The Impact of Pf Bacteriophages on the Fitness of Pseudomonas aeruginosa; A Mathematical Modeling Approach

J. D. Pourtois, M. J. Kratochvil, Q. Chen, N. L. Haddock, E. B. Burgener, G. A. De Leo, P. L. Bollyky

This paper uses a mathematical model to show that Pf+ Pseudomonas aeruginosa strains can outcompete Pf- strains under specific antibiotic conditions, promoting antibiotic tolerance.

bioRxiv · Aug 30, 2020 · PreprintMicrobiology