M. Kane

Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration

This study shows that sequential binding of CypA and CPSF6 to HIV-1 capsid is necessary for nuclear entry and integration, and that lenacapavir targets this process.

Virus specificity and nucleoporin requirements for MX2 activity are affected by GTPase function and capsid-CypA interactions

This study shows that MX2 antiviral activity depends on CypA-CA interactions and GTPase function, with loss of GTPase activity altering Nup requirements for viral restriction.

Genetic differences between 129S substrains affect antiretroviral immune responses

The paper identifies genetic differences in 129S substrains that affect their ability to mount antiretroviral immune responses against MLV.

Interplay between historical and current features of the cityscape in shaping the genetic structure of the house mouse (Mus musculus domesticus) in Dakar (Senegal, West Africa)

This study examines how historical and current cityscape features shape the genetic structure of house mice in Dakar, finding that both past colonization and present urbanization influence genetic patterns.