A Cytoskeletal Function for PBRM1 Reading Methylated Microtubules
M. Karki, R. K. Jangid, R. N. H. Seervai, J.-P. Bertocchio, T. Hotta, P. Msaouel, S. Y. Jung, S. L. Grimm, C. Coarfa, B. E. Weissman, R. Ohi, K. J. Verhey, C. H. Hodges, R. Dere, I.-Y. Park, , D. N. Tripathi
This study identifies PBRM1 as the first cytoskeletal reader for SETD2-mediated -tubulin methylation, revealing a new role for PBRM1 in mitotic spindle organization and genomic stability.
Science Advances · Apr 2, 2021Peer-reviewedCell Biology