Author

M. Kelley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Bioengineering· 1 Cancer Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

J. B. Benoit· 3 shared C. Herbert· 2 shared P. A. Limbach· 2 shared A. Bonetto· 1 shared A. Cox· 1 shared A. G. Robling· 1 shared A. L. Ankrum· 1 shared A. L. Mosley· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersBiochemistry

J. B. Benoit

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Tyrosine transfer RNA levels and modifications during blood-feeding and vitellogenesis in the mosquito, Aedes aegypti

M. Kelley, C. J. Holmes, C. Herbert, A. Rayhan, J. Joves, R. Frigard, K. Singh, P. A. Limbach, B. Addepalli, J. B. Benoit

The paper examines tRNA abundance and modifications in Aedes aegypti during blood-feeding and vitellogenesis, finding increased tyrosine tRNA transcription is critical for egg yolk protein synthesis.

bioRxiv · Nov 29, 2023 · PreprintBiochemistry

Gemcitabine plus nab-paclitaxel preserves skeletal and cardiac mass and function in a murine model of pancreatic cancer cachexia

A. Narasimhan, D. Jengelley, J. Huot, T. Umberger, E. Doud, A. L. Mosley, M. Wang, X. Zhong, B. Counts, J. Rupert, A. Young, A. Bonetto, D. Horan, A. G. Robling, M. Fishel, , T. Zimmers

This study shows that gemcitabine plus nab-paclitaxel reduces tumor burden and prevents muscle and cardiac wasting in a murine model of pancreatic cancer cachexia.

bioRxiv · Apr 15, 2023 · PreprintCancer Biology

Reduced male fertility of an Antarctic mite following extreme heat stress could prompt localized population declines

J. B. Benoit, G. Finch, A. L. Ankrum, J. Niemantsverdriet, B. Paul, M. Kelley, J. D. Gantz, R. E. Lee, D. L. Denlinger

This study shows that extreme heat stress reduces male fertility in Antarctic mites, potentially leading to population declines.

bioRxiv · Apr 11, 2023Physiology

Pseudomonas aeruginosa Elicits Sustained IL-1β Upregulation in Alveolar Macrophages from Lung Transplant Recipients

N. Britton, A. V. Rueda, S. A. Whiteside, J. Mathew, M. Kelley, S. Agbor-Enoh, J. McDyer, J. D. Christie, R. G. Collman, A. Cox, P. Shah, F. D'Alessio

This study shows that Pseudomonas aeruginosa and its dominant microbiota increase IL-1β production in alveolar macrophages from lung transplant recipients, which can be reduced by inflammasome inhibitors.

bioRxiv · Apr 26, 2022 · PreprintImmunology

Abundances of transfer RNA modifications and transcriptional levels for tRNA-modifying enzymes are sex-specific in mosquitoes

M. Kelley, M. R. Uhran, C. Herbert, G. Yoshida, E. Watts, P. A. Limbach, J. B. Benoit

The paper examines sex-specific differences in tRNA modifications and their associated enzymes in three mosquito species, finding higher modification levels and enzyme expression in females.

bioRxiv · Aug 3, 2021Biochemistry

Massively Multiplexed Affinity Characterization of Therapeutic Antibodies Against SARS-CoV-2 Variants

E. Engelhart, R. Lopez, R. Emerson, C. Lin, C. Shikany, D. Guion, M. Kelley, D. Younger

The paper measures binding affinities of 33 therapeutic antibodies against SARS-CoV-2 variants to identify epitopes and predict future efficacy against RBD mutations.

bioRxiv · Apr 27, 2021Bioengineering