Author

M. Kuchersky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Saragovi· 2 shared E. Gottlieb· 2 shared I. Abramovich· 2 shared M. Berger· 2 shared A. Drori· 1 shared A. S. Wentink· 1 shared A. Swisa· 1 shared B. Bukau· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

A. Saragovi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A unique chaperoning mechanism in Class A JDPs recognizes and stabilizes mutant p53.

G. Zoltsman, T. L. Dang, M. Kuchersky, O. Faust, M. S. Silva, T. Ilani, A. S. Wentink, B. Bukau, R. Rosenzweig

This study identifies a unique chaperoning mechanism in class-A JDPs that recognizes and stabilizes mutant p53, promoting cancer progression by preventing its degradation.

bioRxiv · Nov 28, 2023Biochemistry

Enhanced methionine cycle suppresses naïve CD8+ T-cell maturation

A. Saragovi, X. Zheng, I. Abramovich, L. Cohen-Daniel, L. Zhuoning, H. Raifer, I. Omar, A. Swisa, M. Kuchersky, A. Drori, F. Marini, O. Toker, R. Somech, C. Schmidl, R. C. Hendrickson, , M. Berger

This study identifies an accelerated methionine cycle in immature CD8+ T cells that suppresses their maturation and immune response, showing that inhibiting the cycle promotes maturation and immune recovery.

bioRxiv · Aug 16, 2022 · PreprintImmunology

Cellular water analysis in T cells reveals a switch from metabolic water gain to water influx

A. Saragovi, T. Zilberman, G. Yasur, K. Turjeman, I. Abramovich, M. Kuchersky, E. Gottlieb, Y. Barenholz, M. Berger

This study uses a novel method to analyze water content in T cells and finds a shift from metabolic water gain to extracellular water influx during cell growth.

bioRxiv · May 11, 2020 · PreprintBiochemistry