L. Zhuoning

β2 integrins impose a mechanical checkpoint on macrophage phagocytosis

This study shows that β2 integrins regulate macrophage phagocytosis based on cargo rigidity, acting as a mechanical checkpoint to control engulfment strategies.

Enhanced methionine cycle suppresses naïve CD8+ T-cell maturation

This study identifies an accelerated methionine cycle in immature CD8+ T cells that suppresses their maturation and immune response, showing that inhibiting the cycle promotes maturation and immune recovery.