Author

M. L. Husby

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Assay:electronic health records· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

R. V. Stahelin· 4 shared S. Amiar· 3 shared P. P. Chapagain· 2 shared A. Heiner· 1 shared A. Maisner· 1 shared A. Marzi· 1 shared B. Lee· 1 shared B. S. Gerstman· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersMicrobiology

R. V. Stahelin

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Author profile →

4 papers

Recent·Most cited

Integrity of membrane fluidity and fatty acid environment are necessary for Ebola virus VP40 assembly and release of viral particles

S. Amiar, K. A. Johnson, M. L. Husby, A. Marzi, R. V. Stahelin

This study shows that membrane fluidity and fatty acid composition are critical for Ebola virus VP40 assembly and viral particle release.

bioRxiv · Aug 24, 2022 · PreprintMicrobiology

Molecular assembly of measles and Nipah virus: specific lipid binding drives conformational change and matrix polymerization

M. J. Norris, M. L. Husby, W. B. Kiosses, J. Yin, L. J. Rennick, A. Heiner, S. S. Harkins, R. Pokhrel, S. L. Schendel, K. M. Hastie, S. Landeras-Bueno, Z. Li Salie, B. Lee, P. P. Chapagain, A. Maisner, , E. Ollmann Saphire

This study identifies how measles and Nipah virus M proteins bind specific lipids, inducing conformational changes that drive virion assembly.

bioRxiv · Oct 11, 2021 · PreprintMicrobiology

The Ebola virus matrix protein clusters phosphatidylserine, a critical step in viral budding

M. L. Husby, S. Amiar, L. I. Prugar, E. A. David, C. B. Plescia, K. E. Huie, J. M. Brannan, J. M. Dye, E. Pienaar, R. V. Stahelin

This study shows that the Ebola virus matrix protein eVP40 clusters phosphatidylserine to promote viral budding, and that fendiline reduces this clustering, inhibiting virus production and entry.

bioRxiv · Jun 8, 2021 · PreprintMicrobiology

Lipid-specific protein oligomerization is regulated by two interfaces in Marburg virus matrix protein VP40

S. Amiar, M. L. Husby, K. J. Wijesinghe, S. Angel, N. Bhattarai, B. S. Gerstman, P. P. Chapagain, S. Li, R. V. Stahelin

This study identifies two distinct oligomerization interfaces in Marburg virus VP40 that regulate lipid-specific protein oligomerization and matrix assembly at the plasma membrane.

bioRxiv · Nov 13, 2020Microbiology