R. V. Stahelin

Minor changes in electrostatics robustly increase VP40 membrane binding, assembly, and budding of Ebola virus matrix protein derived virus-like particles

This study shows that minor electrostatic changes in VP40 significantly affect membrane binding, assembly, and budding of Ebola virus-like particles.

The SARS-CoV-2 nucleoprotein associates with anionic lipid membranes

This study identifies the SARS-CoV-2 nucleoprotein's ability to bind anionic lipids, supporting a model for its role in viral membrane association during assembly.

Integrity of membrane fluidity and fatty acid environment are necessary for Ebola virus VP40 assembly and release of viral particles

This study shows that membrane fluidity and fatty acid composition are critical for Ebola virus VP40 assembly and viral particle release.

Contribution of the Golgi apparatus in morphogenesis of a virus induced cytopathic vacuolar system

The paper investigates how the Golgi apparatus transforms into cytopathic vacuoles during alphavirus infection using electron tomography and Golgi markers.

Molecular assembly of measles and Nipah virus: specific lipid binding drives conformational change and matrix polymerization

This study identifies how measles and Nipah virus M proteins bind specific lipids, inducing conformational changes that drive virion assembly.

The Ebola virus matrix protein clusters phosphatidylserine, a critical step in viral budding

This study shows that the Ebola virus matrix protein eVP40 clusters phosphatidylserine to promote viral budding, and that fendiline reduces this clustering, inhibiting virus production and entry.

Lipid-specific protein oligomerization is regulated by two interfaces in Marburg virus matrix protein VP40

This study identifies two distinct oligomerization interfaces in Marburg virus VP40 that regulate lipid-specific protein oligomerization and matrix assembly at the plasma membrane.

SARS-CoV-2 viral budding and entry can be modeled using virus-like particles

This study develops a BSL-2-compatible system using SARS-CoV-2 virus-like particles to model viral budding and entry mechanisms and assess drug inhibitors.