Author

M. Leibundgut

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

N. Ban· 4 shared A. Scaiola· 2 shared T. Schoenhut· 2 shared A. Brkic· 1 shared A. Filipovska· 1 shared A. J. P. Scott· 1 shared A. Marsavelski· 1 shared A. Steinauer· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersBiochemistry

N. Ban

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4 papers

Recent·Most cited

Universal features of Nsp1-mediated translational shutdown by coronaviruses

K. Schubert, E. D. Karousis, I. Ban, C. Lapointe, M. Leibundgut, E. Baeumlin, E. Kummerant, A. Scaiola, T. Schoenhut, J. Ziegelmueller, J. Puglisi, O. Muehlemann, N. Ban

This study investigates Nsp1-mediated translational shutdown in three Betacoronaviruses, revealing a conserved mechanism and identifying how Nsp1 allows viral mRNA translation.

bioRxiv · May 31, 2023Biochemistry

Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif

A. Brkic, M. Leibundgut, J. Jablonska, V. Zanki, Z. Car, V. Petrovic-Perokovic, A. Marsavelski, N. Ban, I. Gruic-Sovulj

The paper identifies a structural basis for mupirocin resistance in IleRS2, showing that an altered HIGH motif leads to hyper-resistance.

bioRxiv · Jan 31, 2023Biochemistry

Stepwise maturation of the peptidyl transferase region of human mitoribosomes

T. Lenarcic, M. Jaskolowski, M. Leibundgut, A. Scaiola, T. Schoenhut, M. Saurer, R. Lee, O. Rackham, A. Filipovska, N. Ban

The paper identifies key assembly factors and their roles in the maturation of the peptidyl transferase region in human mitoribosomes.

bioRxiv · Mar 29, 2021Biochemistry

Evolution of a virus-like architecture and packaging mechanism in a repurposed bacterial protein

S. Tetter, N. Terasaka, A. Steinauer, R. J. Bingham, S. Clark, A. J. P. Scott, N. Patel, M. Leibundgut, E. Wroblewski, N. Ban, P. G. Stockley, R. Twarock, D. Hilvert

This study evolved a bacterial protein into an artificial nucleocapsid that packages and protects mRNA, revealing evolutionary parallels to viruses and potential applications in vaccine delivery.

bioRxiv · Dec 23, 2020Biochemistry