Author

M. Luis Rodriguez

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Adolfo García‐SastreiD· 2 shared Briana Lynn McGoverniD· 2 shared Kris M. WhiteiD· 2 shared Romel RosalesiD· 2 shared Abdullah M. SyediD· 1 shared Adrian PeliniD· 1 shared Ajda RojciD· 1 shared Alicia RichardsiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPharmacology & Toxicology

Adolfo García‐SastreORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

MDL-001: an Oral, Direct-Acting Broad-Spectrum Antiviral for Influenza-Like Illness (ILI) and Chronic Hepatitis In Vivo

Virgil L. Woods, Tyler J. Umansky, Sean M. Russell, Asha Z. Goodman, Michael D. Bobardt, Briana Lynn McGovern, Romel Rosales, M. Luis Rodriguez, Harm van Bakel, Emilia Mia Sordillo, Viviana R. Simon, Adolfo García‐Sastre, Kris M. White, Philippe A. Gallay, Davey Smith, Daniel J. Haders

This paper evaluates MDL-001, a broad-spectrum antiviral, showing potent in vitro and in vivo activity against influenza, RSV, SARS-CoV-2, and hepatitis B/C/D viruses, with improved efficacy compared to existing treatments.

Pharmaceuticals · Oct 18, 2026Peer-reviewedPharmacology & Toxicology

Global landscape of the host response to SARS-CoV-2 variants reveals viral evolutionary trajectories

Mehdi Bouhaddou, Ann‐Kathrin Reuschl, Benjamin J. Polacco, Lucy Thorne, Manisha R. Ummadi, Chengjin Ye, Romel Rosales, Adrian Pelin, Jyoti Batra, Gwendolyn Μ. Jang, Jiewei Xu, Jack M. Moen, Alicia Richards, Yuan M. Zhou, Bhavya Harjai, , Nevan J. Krogan

The paper systematically analyzes proteomic and genomic data of SARS-CoV-2 variants to identify how mutations affect viral gene expression, host interactions, and immune evasion.

bioRxiv · Oct 19, 2022 · PreprintSystems Biology