Author

M. Madern

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

M. Hartl· 3 shared W. Ellmeier· 3 shared W. Reiter· 3 shared C. Bock· 2 shared C. Zhu· 2 shared M. Alteneder· 2 shared N. Boucheron· 2 shared A. Hagelkrueys· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersImmunology

M. Hartl

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Single-cell profiling uncovers regulatory programs of pathogenic Th2 cells in allergic asthma

M. Khan, M. Alteneder, W. Reiter, T. Krausgruber, L. Dobnikar, M. Madern, M. Waldherr, C. Bock, M. Hartl, W. Ellmeier, J. Henriksson, N. Boucheron

This study uses scRNA-seq to identify two distinct subsets of pathogenic Th2 cells in allergic asthma and establishes an in vitro model to study their regulation.

bioRxiv · Aug 10, 2023Immunology

Targeting the catalytic activity of HDAC1 in T cells protects against experimental autoimmune encephalomyelitis

C. Zhu, V. Stolz, N. Simonovic, O. Al-Rubaye, T. Vcelkova, V. Moos, L. Hess, A. Hagelkrueys, M. Madern, W. Reiter, A. Meixner, C. Bock, M. Hartl, W. Ellmeier, C. Seiser

This study shows that inhibiting HDAC1 catalytic activity in T cells prevents experimental autoimmune encephalomyelitis by reducing proinflammatory cytokines and effector functions.

bioRxiv · Apr 14, 2023 · PreprintImmunology

The guanine nucleotide exchange factor Rin-like acts as a gatekeeper for T follicular helper cell differentiation via regulating CD28 signaling

L. Sandner, M. Alteneder, R. Rica, B. Woller, E. Sala, T. Frey, A. Tosevska, C. Zhu, M. Madern, P. Hoffmann, A. Schebesta, I. Taniuchi, M. Bonelli, K. Schmetterer, M. Iannacone, , N. Boucheron

This study identifies Rin-like as a negative regulator of Tfh differentiation in mice and humans, showing its role in CD28 signaling and endocytosis.

bioRxiv · Jun 23, 2022Immunology

In search of the universal method: a comparative survey of bottom-up proteomics sample preparation methods

G. Varnavides, M. Madern, D. Anrather, N. Hartl, W. Reiter, M. Hartl

The paper compares 16 bottom-up proteomics sample preparation methods to identify optimal strategies for protein extraction and MS analysis.

bioRxiv · May 4, 2022Biochemistry