Author

M. P. Levesque

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:batch correction / integration· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Samarkina· 2 shared B. Bodenmiller· 2 shared G.-P. Dotto· 2 shared M. Ma· 2 shared S. Ghosh· 2 shared A. Clocchiatti· 1 shared A. Jacobs· 1 shared A. Katarkar· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersCancer Biology

A. Samarkina

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Author profile →

4 papers

Recent·Most cited

Standardization of suspension and imaging mass cytometry readouts for clinical decision making

R. Casanova, S. Xu, S. Sivapatham, A. Jacobs, S. Engler, Tumor Profiler Consortium, M. P. Levesque, R. Dummer, B. Bodenmiller, S. Chevrier

This study standardizes suspension and imaging mass cytometry measurements to improve clinical reproducibility and provide oncologists with tumor biology insights.

bioRxiv · Mar 19, 2023 · PreprintCancer Biology

Androgen Receptor is a Determinant of Melanoma Targeted Drug Resistance

A. Samarkina, M. K. Youssef, P. Ostano, S. Ghosh, M. Ma, B. Tassone, T. Proust, G. Chiorino, M. P. Levesque, G.-P. Dotto

This study shows that androgen receptor activity contributes to melanoma resistance to BRAF/MEK inhibitors and suggests targeting AR could improve treatment outcomes.

bioRxiv · May 27, 2022Cancer Biology

Multiplexed Imaging Mass Cytometry of Chemokine Milieus in Metastatic Melanoma Characterizes Features of Response to Immunotherapy

T. Hoch, D. Schulz, N. Eling, J. Martlnez Gomez, M. P. Levesque, B. Bodenmiller

The paper characterizes chemokine landscapes in metastatic melanoma using multiplexed imaging mass cytometry, linking chemokine expression to immune infiltration and response to immunotherapy.

bioRxiv · Jul 29, 2021Cancer Biology

Sustained Androgen Receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis

M. Ma, S. Ghosh, D. Tavernari, A. Katarkar, A. Clocchiatti, L. Mazzeo, A. Samarkina, J. Epiney, Y.-R. Yu, P.-C. Ho, M. P. Levesque, B. Özdemir, G. Ciriello, R. Dumme, G.-P. Dotto

This study shows that androgen receptor signaling promotes melanoma cell growth and tumorigenesis, with AR inhibition reducing proliferation, enhancing DNA repair, and inducing immune responses.

bioRxiv · May 26, 2020Cancer Biology