Author

L. Mazzeo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

G.-P. Dotto· 3 shared S. Ghosh· 2 shared A. Clocchiatti· 1 shared A. Katarkar· 1 shared A. P. Bowman· 1 shared A. Samarkina· 1 shared A. Toniolo· 1 shared B. Özdemir· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCancer Biology

G.-P. Dotto

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Author profile →

3 papers

Recent·Most cited

Nuclear lamin A/C phosphorylation by loss of Androgen Receptor is a global determinant of cancer-associated fibroblast activation.

S. Ghosh, J. Isma, L. Mazzeo, A. Toniolo, C. Simon, G.-P. Dotto

This study shows that loss of androgen receptor increases lamin A/C phosphorylation, driving cancer-associated fibroblast activation through transcriptional changes.

bioRxiv · Jun 28, 2023 · PreprintCancer Biology

Sphingolipid Control of Fibroblast Heterogeneity Revealed by Single-Cell Lipidomics

L. Capolupo, I. Khven, L. Mazzeo, G. Glousker, F. Russo, J. Paz Montoya, S. Ho, D. R. Bhandari, A. P. Bowman, S. Ellis, R. Guiet, J. Muthing, B. Spengler, R. M. A. Heeren, G.-P. Dotto, , G. D'Angelo

This study identifies sphingolipid composition as a driver of fibroblast heterogeneity and state transitions using single-cell lipidomics and transcriptomics.

bioRxiv · Feb 23, 2021 · PreprintBiochemistry

Sustained Androgen Receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis

M. Ma, S. Ghosh, D. Tavernari, A. Katarkar, A. Clocchiatti, L. Mazzeo, A. Samarkina, J. Epiney, Y.-R. Yu, P.-C. Ho, M. P. Levesque, B. Özdemir, G. Ciriello, R. Dumme, G.-P. Dotto

This study shows that androgen receptor signaling promotes melanoma cell growth and tumorigenesis, with AR inhibition reducing proliferation, enhancing DNA repair, and inducing immune responses.

bioRxiv · May 26, 2020Cancer Biology