Author

Y.-R. Yu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

P.-C. Ho· 2 shared A. Clocchiatti· 1 shared A. Katarkar· 1 shared A. Samarkina· 1 shared A. Swain· 1 shared B. A. Howard· 1 shared B. Özdemir· 1 shared D. Bratton· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

P.-C. Ho

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Macrophage Xanthine Oxidoreductase Links LPS Induced Lung Inflammatory Injury to NLRP3 Inflammasome Expression and Mitochondrial Respiration

M. A. Fini, J. A. Monks, M. Li, E. Gerasimovskaya, P. Paucek, K. Wang, M. G. Frid, S. C. Pugliese, D. Bratton, Y.-R. Yu, D. Irwin, M. Karin, R. M. Wright, K. R. Stenmark

This study shows that macrophage-specific Xanthine Oxidoreductase (XOR) exacerbates LPS-induced lung injury by promoting NLRP3 inflammasome expression and glycolytic metabolism in inflammatory macrophages.

bioRxiv · Jul 21, 2023 · PreprintImmunology

Sustained Androgen Receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis

M. Ma, S. Ghosh, D. Tavernari, A. Katarkar, A. Clocchiatti, L. Mazzeo, A. Samarkina, J. Epiney, Y.-R. Yu, P.-C. Ho, M. P. Levesque, B. Özdemir, G. Ciriello, R. Dumme, G.-P. Dotto

This study shows that androgen receptor signaling promotes melanoma cell growth and tumorigenesis, with AR inhibition reducing proliferation, enhancing DNA repair, and inducing immune responses.

bioRxiv · May 26, 2020Cancer Biology

A mouse SWATH-MS reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts

L. Krasny, P. Bland, J. Burns, N. C. Lima, P. T. Harrison, L. Pacini, M. L. Elms, J. Ning, V. G. Martinez, Y.-R. Yu, S. E. Acton, P.-C. Ho, F. Calvo, A. Swain, B. A. Howard, , P. H. Huang

The paper develops a mouse SWATH-MS spectral library and a deconvolution method to analyze proteomic changes in human tumor xenografts, revealing host-tumor interactions.

bioRxiv · Feb 3, 2020Biochemistry