ImmunologybioRxivPreprint
Hsa-miR-31-5p controls a metabolic switch in psoriatic keratinocytes that identifies therapeutic intervention
M. Wang, Y. Yong, H. Vos…·B. M. Burgering
This study shows that miR-31-5p in psoriatic keratinocytes promotes a metabolic switch to glutamine metabolism, leading to immune-modulatory effects and Th17 cell differentiation, which can be inhibited by GLS targeting.
DOI 10.1101/2022.01.21.477183