Author

B. M. Burgering

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

E. C. A. Stigter· 2 shared M. C. Gulersonmez· 2 shared C. Lu· 1 shared H. C. Clevers· 1 shared H. Deng· 1 shared H. Vos· 1 shared J. Drost· 1 shared J. Gerrits· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

E. C. A. Stigter

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Author profile →

2 papers

Recent·Most cited

Hsa-miR-31-5p controls a metabolic switch in psoriatic keratinocytes that identifies therapeutic intervention

M. Wang, Y. Yong, H. Vos, M. C. Gulersonmez, E. C. A. Stigter, J. Gerrits, M. Pages Gallego, R. van Es, L. Li, H. Deng, L. Han, R. Huang, C. Lu, B. M. Burgering

This study shows that miR-31-5p in psoriatic keratinocytes promotes a metabolic switch to glutamine metabolism, leading to immune-modulatory effects and Th17 cell differentiation, which can be inhibited by GLS targeting.

bioRxiv · Jan 21, 2022 · PreprintImmunology

Rewiring glucose metabolism improves 5-FU efficacy in glycolytic p53-deficient colorectal tumors

M. C. Ludikhuize, S. Gevers, N. T. B. Nguyen, M. Meerlo, S. K. Shafiei Roudbari, M. C. Gulersonmez, E. C. A. Stigter, J. Drost, H. C. Clevers, B. M. Burgering, M. J. RodrIguez-Colman

This study shows that rewiring glucose metabolism enhances 5-FU efficacy in p53-deficient colorectal tumors by altering nucleotide pools without increasing toxicity in healthy cells.

bioRxiv · Nov 11, 2021Cancer Biology