Author

M. R. Ransom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. E. Gillen· 2 shared B. M. Stevens· 2 shared C. T. Jordan· 2 shared A. A. Bauman· 1 shared A. Hiron· 1 shared A. Hoppers· 1 shared A. I. Sheth· 1 shared A. Krug· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

A. E. Gillen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Targeting Acute Myeloid Leukemia Stem Cells Through Perturbation of Mitochondrial Calcium

A. I. Sheth, K. Engel, H. Tolison, M. J. Althoff, M. L. Amaya, A. Krug, T. Young, S. Pei, S. B. Patel, M. Minhajuddin, A. Winters, R. Miller, I. Shelton, J. St-Germain, T. Ling, , C. T. Jordan

This study identifies mitochondrial calcium utilization as a metabolic requirement of venetoclax-resistant acute myeloid leukemia stem cells and shows that targeting mitochondrial calcium uptake can eradicate these cells.

bioRxiv · Oct 2, 2023Cancer Biology

Transcriptional adaptation of drug-tolerant Mycobacterium tuberculosis in mice

E. A. Wynn, C. Dide-Agossou, M. Reichlen, K. Rossmassler, R. Al Mubarak, J. J. Reid, S. T. Tabor, S. E. Born, M. R. Ransom, R. M. Davidson, K. N. Walton, J. B. Benoit, A. Hoppers, A. A. Bauman, L. M. Massoudi, , N. D. Walter

This study develops a targeted amplification RNA sequencing method, SEARCH-TB, to analyze Mycobacterium tuberculosis transcriptomes in mice during treatment, revealing transcriptional adaptations including metabolic shifts and regulatory reprogramming.

bioRxiv · Mar 6, 2023Microbiology

MuVEH and mitoMuVEH improve discovery of genetic variation from single cells.

M. R. Ransom, K. L. Engel, B. M. Stevens, C. T. Jordan, A. E. Gillen

MuVEH and mitoMuVEH enhance variant detection in scRNA-seq and enable clonal relationship reconstruction in AML patients.

bioRxiv · Nov 22, 2022 · PreprintCancer Biology

Identification of zinc-dependent mechanisms used by Group B Streptococcus to overcome calprotectin-mediated stress

L. R. Burcham, Y. Le Breton, J. N. Radin, B. Spencer, L. Deng, A. Hiron, M. R. Ransom, J. d. C. Mendonca, A. T. Belew, N. M. El-Sayed, K. S. McIver, T. E. Kehl-Fie, K. Doran

This study identifies zinc-dependent mechanisms in Group B Streptococcus that allow it to survive calprotectin-mediated metal starvation and cause invasive disease.

bioRxiv · Aug 14, 2020Microbiology