Author

Y. Le Breton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:non-human primate· 1 Assay:proteomics· 1

Frequent Co-Authors

K. S. McIver· 3 shared A. T. Belew· 2 shared G. Lambeau· 2 shared N. M. El-Sayed· 2 shared N. M. van Sorge· 2 shared V. P. van Hensbergen· 2 shared A. G. McEwan· 1 shared A. G. Turner· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMicrobiology

K. S. McIver

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Identification of zinc-dependent mechanisms used by Group B Streptococcus to overcome calprotectin-mediated stress

L. R. Burcham, Y. Le Breton, J. N. Radin, B. Spencer, L. Deng, A. Hiron, M. R. Ransom, J. d. C. Mendonca, A. T. Belew, N. M. El-Sayed, K. S. McIver, T. E. Kehl-Fie, K. Doran

This study identifies zinc-dependent mechanisms in Group B Streptococcus that allow it to survive calprotectin-mediated metal starvation and cause invasive disease.

bioRxiv · Aug 14, 2020Microbiology

Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides

R. J. Edgar, V. P. van Hensbergen, A. Ruda, A. G. Turner, P. Deng, Y. Le Breton, N. M. El-Sayed, A. T. Belew, K. S. McIver, A. G. McEwan, A. J. Morris, G. Lambeau, M. J. Walker, J. S. Rush, K. V. Korotkov, , N. Korotkova

The paper identifies a glycerol phosphate modification on streptococcal rhamnose polysaccharides, revealing its role in host-pathogen interactions and vaccine design.

bioRxiv · Jan 27, 2019Microbiology

Streptococcal Lancefield polysaccharides are critical cell wall determinants for human group IIA secreted phospholipase A2 to exert its bactericidal effects

V. P. van Hensbergen, E. Movert, V. de Maat, C. Luechtenborg, Y. Le Breton, G. Lambeau, C. Payre, A. Henningham, V. Nizet, J. A. G. Van Strijp, B. Bruegger, F. Carlsson, K. S. McIver, N. M. van Sorge

This study identifies Lancefield polysaccharides as critical for hGIIA to kill Group A and B Streptococcus by enabling penetration through the bacterial cell wall.

bioRxiv · Aug 16, 2018Microbiology