Author

M. Rahbari

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

M. Heikenwalder· 3 shared A. Ali· 1 shared A. Billeter· 1 shared A. Chung· 1 shared A. Collins· 1 shared A. Filby· 1 shared A. Fuller· 1 shared A. Hedley· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCancer Biology

M. Heikenwalder

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4 papers

Recent·Most cited

Single-cell and spatial atlas of steatotic liver-related hepatocellular carcinoma

A. Prawira, H. Xu, W. Q. Leow, M. Otsuka, Z. Chen, M. Rahbari, S. N. Hazirah, M. Wasser, A. Chung, B. K. P. Goh, P. K.-H. Chow, S. Albani, J. Lee, T. Lim, W. Zhai, , V. Chew

This study characterizes the tumor microenvironment of steatotic liver-related hepatocellular carcinoma using single-cell and spatial transcriptomic analyses, identifying immunosuppressive features and Treg-CAF interactions linked to immunotherapy resistance.

bioRxiv · May 9, 2024 · PreprintImmunology

Beneficial effects of intermittent fasting in NASH and subsequent HCC development are executed by concerted PPAR alpha and PCK1 action in hepatocytes

S. Gallage, A. Ali, J. E. Barragan Avila, N. Seymen, P. Ramadori, V. Joerke, L. Zizmare, J. Kosla, X. Li, E. Focaccia, S. Yousuf, T. Sijmonsma, M. Rahbari, K. S. Kommoss, A. Billeter, , M. Heikenwalder

This study shows intermittent fasting prevents NASH and HCC by PPAR alpha and PCK1 working together in liver cells.

bioRxiv · Oct 23, 2023 · PreprintCancer Biology

Mouse mammary tumor virus is implicated in severity of colitis and dysbiosis in the IL-10-/- mouse model of inflammatory bowel disease

H. Armstrong, M. Rahbari, H. Park, D. Sharon, A. Thiesen, N. Hotte, N. Sun, H. Syed, H. Abofayed, W. Wang, K. Madsen, E. Wine, A. Mason

This study investigates the role of mouse mammary tumor virus (MMTV) in colitis and dysbiosis in IL-10-/- mice, finding that MMTV contributes to disease severity and that antiretroviral therapy reduces MMTV load and improves symptoms.

bioRxiv · Jan 26, 2023Microbiology

CXCR2 inhibition enables NASH-HCC immunotherapy

J. Leslie, J. B. G. Mackey, T. Jamieson, E. Ramon-Gil, T. M. Drake, F. Fercoq, W. Clark, K. Gilroy, A. Hedley, C. Nixon, S. Luli, M. Laszczewska, R. Pinyol, R. Esteban-Fabro, C. E. Willoughby, , Carlin

This study shows that combining CXCR2 inhibition with anti-PD1 therapy enhances immunotherapy response in NASH-HCC by reprogramming tumor-associated neutrophils.

bioRxiv · Feb 24, 2022Cancer Biology