Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1
A. K. Cada, M. Remec Pavlin, J. P. Castillo, A. B. Tong, K. P. Larsen, X. Ren, A. L. Yokom, F.-C. Tsai, J. Shiah, P. Bassereau, C. J. Bustamante, J. H. Hurley
This study shows that CHMP1B and IST1 can sever membranes through a friction-driven mechanism, requiring constriction and extensional force, but not VPS4 or spastin.
bioRxiv · Feb 3, 2022 · PreprintBiophysics