Membrane curvature sensing and stabilization by the autophagic LC3 lipidation machinery
L. E. Jensen, S. Rao, M. Schuschnig, A. K. Cada, S. Martens, G. Hummer, J. H. Hurley
The paper investigates how the LC3 lipidation machinery interacts with curved membranes during autophagy initiation, showing that ATG12-5-16L1 stabilizes membrane curvature.
bioRxiv · May 3, 2022Biophysics