M. Rouault

Spatially organized cellular communities shape functional tissue architecture in the pancreas

This study maps pancreatic cell populations across space and time in mice, revealing spatially organized niches and their functional roles in development and adult homeostasis.

High resolution mapping of the breast cancer tumor microenvironment using integrated single cell, spatial and in situ analysis of FFPE tissue

This paper integrates single cell, spatial, and in situ technologies to analyze FFPE breast cancer tissue, revealing molecular insights into tumor subtypes and progression.

Compulsivity is linked to maladaptive choice variability but unaltered reinforcement learning under uncertainty

This study links compulsivity to increased choice variability without changes in learning variability under uncertainty.

The online metacognitive control of decisions

This paper introduces a computational model for online metacognitive control of decisions, showing it reproduces empirical results in value-based decision making.

Adaptive tuning of human learning and choice variability to unexpected uncertainty

This study shows humans adjust exploration and learning precision in response to unexpected uncertainty, demonstrating adaptive tuning of decision-making strategies.

Spatially defined multicellular functional units in colorectal cancer revealed from single cell and spatial transcriptomics

The paper combines single cell and spatial transcriptomics to map spatial organization and functional interactions in colorectal cancer across species.

Transcriptionally defined morphological subtypes of pancreatic ductal adenocarcinoma

The paper identifies five transcriptional subtypes of PDAC cells with distinct morphological patterns and confirms their prognostic significance using bulk RNA-sequencing datasets.