Author

S. Imada

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

O. H. Yilmaz· 3 shared A. Mehta· 1 shared A. Niesnerova· 1 shared A. Regev· 1 shared C. Y. Park· 1 shared D. Breault· 1 shared D. Dionne· 1 shared E. Murray· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

O. H. Yilmaz

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Spatially defined multicellular functional units in colorectal cancer revealed from single cell and spatial transcriptomics

I. Avraham-Davidi, S. Mages, J. Klughammer, N. Moriel, S. Imada, M. Hofree, E. Murray, J. Chen, K. Pelka, A. Mehta, G. M. Boland, T. M. Delorey, L. Caplan, D. Dionne, R. Strasser, , A. Regev

The paper combines single cell and spatial transcriptomics to map spatial organization and functional interactions in colorectal cancer across species.

bioRxiv · Oct 2, 2022Cancer Biology

Lymphatics constitute a novel component of the intestinal stem cell niche

N. Goto, S. Imada, V. Deshpande, O. H. Yilmaz

This study identifies lymphatic endothelial cells (LECs) as a novel component of the intestinal stem cell (ISC) niche, alongside Rspo3+Grem1+ fibroblasts (RGFs), which together provide essential RSPO3 for ISC maintenance and regeneration.

bioRxiv · Jan 28, 2022 · PreprintCell Biology

Stiffness Regulates Intestinal Stem Cell Fate

S. He, L. Peng, W. Kang, P. Cheung, T. Xu, M. Mana, C. Y. Park, H. Wang, S. Imada, J. O. Russell, J. Wang, R. Wang, Z. Zhou, K. Chetal, E. Stas, , N. Saeidi

This study shows that matrix stiffness affects intestinal stem cell fate by reducing Lgr5high ISCs and promoting differentiation into goblet cells, mediated by YAP nuclear translocation.

bioRxiv · Mar 15, 2021Cell Biology