Author

M. Roussel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Ecology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Research Focus:differential expression· 4 Organism:human· 4 Research Focus:cell-cell communication· 3 Assay:flow cytometry· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

J. Ferrant· 3 shared K. Tarte· 3 shared S. Le Gallou· 3 shared A. Bonaud· 2 shared C. Monvoisin· 2 shared C. Pangault· 2 shared C. Sirac· 2 shared J. Pollet· 2 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersImmunology

J. Ferrant

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A mouse model of cardiac AL amyloidosis unveils mechanisms of tissue accumulation and toxicity of amyloid fibrils

G. Martinez-Rivas, M. V. Ayala, S. Bender, G. R. Codo, K. W. Swiderska, A. Lampis, L. Pedroza, M. Merdanovic, P. Sicard, E. Pinault, L. Richard, F. Lavatelli, D. Canetti, A. Rinsant, K. Sihem, , C. Sirac

This paper develops a mouse model of cardiac AL amyloidosis that reproduces human disease features, including amyloid deposits and cardiac dysfunction, and identifies a role for partial LC degradation in fibril formation.

Nature Communications · Mar 27, 2025Peer-reviewedPathology

Disruption of immunoglobulin heavy and light chain assembly by antisense oligonucleotides impairs protein homeostasis and myeloma cell survival

C. Horiot, M. Roussel, A. Praite, J. Pollet, S. Bender, C. Sirac, A. Bonaud, L. Delpy

This study shows that antisense oligonucleotides targeting IgG mRNA reduce IgG secretion in myeloma cells, leading to toxic free-light chain accumulation and cell death.

bioRxiv · Aug 29, 2023 · PreprintImmunology

Prospects and pitfalls of an intrusive model for the Chatelperronian stone tool industry during the Middle to Upper Palaeolithic transition in France and northern Spain

I. Djakovic, M. Soressi, M. Roussel

This paper discusses the pros and cons of a model proposing that the Chatelperronian stone tool industry originated from a migration of Homo sapiens from the Levant to France during the Middle to Upper Palaeolithic transition.

bioRxiv · Jul 14, 2023 · PreprintEcology

Single-cell profiling identifies clinically relevant interactions between tumor associated macrophages and blood endothelial cells in diffuse large B cell lymphoma

J. Ferrant, S. Le Gallou, F. Padonou, S. Leonard, I. Papa, C. Pangault, A. Barthel, V. Launay, G. Manson, B. Hoareau, L. Deleurme, C. Monvoisin, B. Albaud, N. Van Acker, C. Laurent, , M. Roussel

The paper identifies interactions between tumor-associated macrophages and blood endothelial cells in DLBCL using single-cell profiling and confirms their role in an immunosuppressive microenvironment linked to poor prognosis.

bioRxiv · Dec 8, 2022Immunology

Nonclassical monocytes are prone to migrate into tumor in diffuse large B-cell lymphoma

S. Le Gallou, F. Lhomme, J. M. Irish, A. Mingam, C. Pangault, C. Monvoisin, J. Ferrant, I. Azzaoui, D. Rossille, K. Bouabdallah, G. Damaj, G. Cartron, P. Godemer, S. Le Gouill, O. Casanovas, , M. Roussel

The paper assesses monocyte subsets in DLBCL patients, finding that nonclassical monocytes are decreased in peripheral blood and prone to migrate into tumors, correlating with adverse outcomes.

bioRxiv · Apr 10, 2021Immunology

Mass cytometry and artificial intelligence define CD169 as a specific marker of SARS-CoV2-induced acute respiratory distress syndrome

M. Roussel, J. Ferrant, F. Reizine, S. Le Gallou, J. Dulong, S. Carl, M. Lesouhaitier, M. Gregoire, N. Bescher, C. Verdy, M. Latour, I. Bezier, M. Cornic, S. Leonard, J. Feuillard, , K. Tarte

The paper identifies a specific immune signature in COVID-19-associated ARDS using mass cytometry and AI, showing it differs from other ARDS causes and is linked to adverse ICU outcomes.

bioRxiv · Sep 22, 2020Immunology