Author

K. Pozo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. E. Johnson· 2 shared A. Guo· 1 shared A. J. Gill· 1 shared A. M. Carter· 1 shared A. S. Ireland· 1 shared B. L. Witt· 1 shared B. Robinson· 1 shared C. P. Whitney· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

J. E. Johnson

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Author profile →

3 papers

Recent·Most cited

ASCL1 represses a latent osteogenic program in small cell lung cancer in multiple cells of origin

R. R. Olsen, D. W. Kastner, A. S. Ireland, S. M. Groves, K. Pozo, C. P. Whitney, M. R. Guthrie, S. J. Wait, D. Soltero, B. L. Witt, V. Quaranta, J. E. Johnson, T. G. Oliver

This study shows ASCL1 represses a latent osteogenic program in SCLC, promoting tumor initiation and preventing differentiation into bone tumors.

bioRxiv · Nov 11, 2020Cancer Biology

Lineage transcription factors co-regulate subtype-specific genes providing a roadmap for systematic identification of small cell lung cancer vulnerabilities

K. Pozo, R. K. Kollipara, D. P. Kelenis, K. E. Rodarte, X. Zhang, J. D. Minna, J. E. Johnson

This study identifies lineage transcription factors and super-enhancer signatures in SCLC, revealing co-regulation of subtype-specific genes and highlighting ASCL1 as a key dependency.

bioRxiv · Aug 13, 2020 · PreprintCancer Biology

Phosphoprotein-based Biomarkers as Predictors for Cancer Therapy

A. M. Carter, C. Tan, K. Pozo, R. Telange, R. Molinaro, A. Guo, E. De Rosa, J. O. Martinez, S. Zhang, N. Kumar, M. Takahashi, T. Wiederhold, H. K. Ghayee, S. C. Oltmann, K. Pacak, , J. A. Bibb

The paper identifies phosphoprotein biomarkers for Cdk5 activity in neuroendocrine tumors and shows their predictive value for anti-Cdk5 therapy.

bioRxiv · Jun 20, 2019Cancer Biology