M. T. B. Clabbers

This paper introduces a method to prepare lipidic cubic phase (LCP) membrane protein crystals for MicroED by using fluorescence microscopy to identify and mill crystals without converting LCP to sponge phase.

This paper demonstrates the use of K2 and K3 direct electron detectors in electron-counting mode for MicroED data collection, enabling structure determination of macromolecules at resolutions between 1.2 and 2.8 Å.

This study uses MicroED to identify hydrogen atom positions and hydrogen bonding networks in proteins, providing detailed structural insights for drug discovery and structural biology.

The paper determines the structures of two proteins using ab initio phasing with MicroED data collected on a direct electron detector in counting mode.

This study benchmarks the optimal thickness for cryo-EM samples using MicroED, finding that structures can be reliably determined up to twice the inelastic mean free path.