Author
B. L. Nannenga
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
Click to filter author papersSignature Assays, Organisms & Methods
Click to filter · or open tagActivity by Year
2019-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 15 mutual co-author links5 papers
Recent·Most cited
Electron-counting MicroED data with the K2 and K3 direct electron detectors
M. T. B. Clabbers, M. W. Martynowycz, J. Hattne, B. L. Nannenga, T. Gonen
This paper demonstrates the use of K2 and K3 direct electron detectors in electron-counting mode for MicroED data collection, enabling structure determination of macromolecules at resolutions between 1.2 and 2.8 Å.
bioRxiv · Jul 4, 2022Biochemistry
New Structural Insights into the Function of the Catalytically Active Human Taspase1
N. Nagaratnam, S. Delker, R. Jernigan, T. E. Edwards, J. Snider, D. Thifault, D. Williams, B. L. Nannenga, M. Stofega, L. Sambucetti, J. Hsieh, A. J. Flint, P. Fromme, J. M. Martin-Garcia
This study determines the crystal structure of catalytically active human Taspase1 and identifies a long helical domain essential for its enzymatic activity, suggesting it as a potential target for anticancer therapeutics.
bioRxiv · Nov 26, 2020Biochemistry
MicroED structure of the human adenosine receptor determined from a single nanocrystal in LCP
M. W. Martynowycz, A. Shiriaeva, X. Ge, J. Hattne, B. L. Nannenga, V. Cherezov, T. Gonen
The paper determines the structure of the human A2A adenosine receptor using MicroED after converting LCP to sponge phase and cryoFIB milling, achieving 2.8 Å resolution.
bioRxiv · Sep 27, 2020Biophysics
Structure determination from lipidic cubic phase embedded microcrystals by MicroED
L. Zhu, G. Bu, L. Jing, D. Shi, T. Gonen, W. Liu, B. L. Nannenga
This study demonstrates the use of modified LCP and MicroED protocols to determine structures from microcrystals embedded in LCP using proteinase K as a model system.
bioRxiv · Aug 4, 2019Biochemistry