Author

M. Tachedjian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:host-pathogen & immune response· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Organism:Arabidopsis· 1 Organism:bacteria (other)· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. McAuley· 2 shared G. A. Marsh· 2 shared J. D. Druce· 2 shared K. R. Blasdell· 2 shared M. J. Kuiper· 2 shared S. Goldie· 2 shared S. Riddell· 2 shared S. S. Vasan· 2 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. McAuley

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Highly Thermotolerant SARS-CoV-2 Vaccine Elicits Neutralising Antibodies Against Delta and Omicron in Mice

P. Jansen van Vuren, A. J. McAuley, M. J. Kuiper, N. B. Singanallur, M. P. Bruce, S. Riddell, S. Goldie, S. Mangalaganesh, S. Chahal, T. W. Drew, K. R. Blasdell, M. Tachedjian, L. Caly, J. D. Druce, S. Ahmed, , S. S. Vasan

This study evaluates a highly thermotolerant SARS-CoV-2 vaccine in mice, showing it elicits neutralizing antibodies against Delta and Omicron variants.

bioRxiv · Mar 3, 2022Immunology

Live virus neutralisation of the 501Y.V1 and 501Y.V2 SARS-CoV-2 variants following INO-4800 vaccination of ferrets

S. Riddell, S. Goldie, A. McAuley, M. J. Kuiper, P. A. Durr, K. R. Blasdell, M. Tachedjian, J. D. Druce, T. R. F. Smith, K. Broderick, S. S. Vasan

This study evaluates the neutralization of SARS-CoV-2 variants 501Y.V1 and 501Y.V2 by sera from ferrets vaccinated with INO-4800, finding reduced titres against 501Y.V2 compared to G614.

bioRxiv · Apr 17, 2021Immunology

Unique Evolution of Antiviral Tetherin in Bats

J. A. Hayward, M. Tachedjian, A. Johnson, A. T. Irving, T. B. Gordon, J. Cui, A. Nicolas, I. Smith, V. Boyd, G. A. Marsh, M. L. Baker, L.-F. Wang, G. Tachedjian

This study characterizes the evolution of tetherin in bats, identifying unique structural variants and splice isoforms with antiviral functions.

bioRxiv · Apr 8, 2020Evolutionary Biology

Filoviruses Can Efficiently Infect Human Neuron-Like Cells Without Genetic Adaptation

A. McAuley, M. Tachedjian, G. A. Marsh

This study shows filoviruses can infect human neuron-like cells without genetic changes, with Marburg virus persisting longer, suggesting potential for long-term neurological effects.

bioRxiv · Dec 12, 2019 · PreprintMicrobiology

RNASeq analysis of Aedes albopictus mosquitoes during chikungunya virus infection

R. Vedururu, M. J. Neave, M. Tachedjian, P. R. Gorry, J.-B. Duchemin, P. N. Paradkar

This study uses RNASeq to analyze gene expression changes in Aedes albopictus mosquitoes infected with chikungunya virus, identifying differentially expressed genes and viral genomic changes across tissues and timepoints.

bioRxiv · Jul 12, 2018Microbiology