SARS-CoV-2-specific memory B cells can persist in the elderly despite loss of neutralising antibodies
A. Jeffery-Smith, A. R. Burton, S. Lens, C. Rees-Spear, M. Patel, R. Gopal, L. Muir, F. Aiano, K. J. Doores, J. Y. Chow, S. N. Ladhani, M. Zambon, L. E. McCoy, M. K. Maini
Circulating class-switched spike and RBD-specific memory B cells can outlast detectable neutralising antibodies but are functionally constrained in the elderly.
bioRxiv · May 30, 2021 · PreprintImmunology