M. Galiano

Plasma membrane abundance dictates phagocytic capacity and functional crosstalk in myeloid cells

This study shows that plasma membrane abundance regulates phagocytic capacity and post-phagocytic migration in myeloid cells, with G{beta}4 deficiency leading to increased phagocytosis and altered trafficking.

Topographical analysis of immune cell interactions reveals a biomechanical signature for immune cytolysis

The paper analyzes immune cell interactions using traction force microscopy to identify biomechanical features associated with cytotoxic T cell activity.

Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model

The paper evaluates the fitness of baloxavir-resistant influenza A viruses in ferrets, finding reduced within-host fitness for A/H3N2 I38T and lower between-host fitness for A/H1N1pdm09 I38T compared to wild-type viruses.

Favipiravir-resistant influenza A virus shows potential for transmission

This study shows favipiravir-resistant influenza A virus can transmit in ferrets but may lose its resistance mutation in vivo due to fitness trade-offs.

Determining the Mutation Bias of Favipiravir in Influenza Using Next-generation Sequencing

This study uses next-generation sequencing to determine the mutation bias caused by favipiravir in influenza virus RNA, showing it primarily acts as a guanine analogue and secondarily as an adenine analogue.