Author

M. K. Maini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:human· 4 Assay:proteomics· 2 Assay:flow cytometry· 1 Organism:virus· 1

Frequent Co-Authors

A. J. Mentzer· 2 shared G. Liu· 2 shared J. C. Knight· 2 shared R. Brown· 2 shared T. Dong· 2 shared X. Yao· 2 shared Y. Peng· 2 shared A. Angyal· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersImmunology

A. J. Mentzer

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Long-term respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination

E. Mitsi, M. O. Diniz, J. Reine, A. M. Collins, R. Robinson, A. Hyder-Wright, M. Farrar, K. Liatsikos, J. Hamilton, O. Onyema, B. C. Urban, C. Solorzano, T. Lambe, S. J. Draper, D. Weiskopf, , D. M. Ferreira

This study shows that hybrid immunity from infection plus vaccination generates durable lung mucosal immunity, while peripheral vaccination alone does not.

bioRxiv · Jan 25, 2023 · PreprintImmunology

Large clones of pre-existing T cells drive early immunity against SARS-COV-2 and LCMV infection.

M. Milighetti, Y. Peng, C. C. S. Tan, M. Mark, G. Nageswaran, S. Byrne, T. Ronel, T. Peacock, A. Mayer, A. Chandran, J. Rosenheim, M. Wheelan, X. Yao, G. Liu, S. L. Felce, , B. Chain

The paper identifies high frequency naive T cell precursors that drive rapid T cell responses during early SARS-COV-2 and LCMV infections.

bioRxiv · Nov 8, 2022Immunology

An ACAT inhibitor regulates SARS-CoV-2 replication and antiviral T cell activity

N. M. Schmidt, P. A. Wing, R. Peters, R. Brown, H. Wang, L. Swadling, J. Newman, N. Thakur, K. Shionoya, S. B. Morgan, T. S. Hinks, K. Watashi, D. Bailey, S. B. Hansen, M. K. Maini, J. A. McKeating

This paper shows that ACAT inhibitors like Avasimibe reduce SARS-CoV-2 replication and enhance antiviral T cell activity in patients.

bioRxiv · Apr 12, 2022 · PreprintImmunology

SARS-CoV-2-specific memory B cells can persist in the elderly despite loss of neutralising antibodies

A. Jeffery-Smith, A. R. Burton, S. Lens, C. Rees-Spear, M. Patel, R. Gopal, L. Muir, F. Aiano, K. J. Doores, J. Y. Chow, S. N. Ladhani, M. Zambon, L. E. McCoy, M. K. Maini

Circulating class-switched spike and RBD-specific memory B cells can outlast detectable neutralising antibodies but are functionally constrained in the elderly.

bioRxiv · May 30, 2021 · PreprintImmunology

The impact of viral mutations on recognition by SARS-CoV-2 specific T-cells

T. I. de Silva, G. Liu, B. B. Lindsey, D. Dong, D. Shah, A. J. Mentzer, A. Angyal, R. Brown, M. D. Parker, Z. Yin, X. Yao, L. Turtle, S. Dunachie, COVID-19 Genomics UK (COG-UK) Consortium, M. K. Maini, , T. Dong

The paper identifies SARS-CoV-2 T-cell epitope variants that reduce recognition by T-cells, highlighting the risk of immune evasion.

bioRxiv · Apr 8, 2021Immunology