Author

J. M. Thornton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Evolutionary Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:statistical model· 2 Organism:C. elegans· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

L. Partridge· 2 shared A. Elofsson· 1 shared A. Frost· 1 shared A. O. Zalevsky· 1 shared A. S. Dunham· 1 shared A. Shenoy· 1 shared A. Stein· 1 shared A. Valencia· 1 shared

Activity by Year

2016-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersEvolutionary Biology

L. Partridge

Author profile →

3 papers

Recent·Most cited

A structural biology community assessment of AlphaFold 2 applications

M. Akdel, D. E. Pires, E. Porta-Pardo, J. Janes, A. O. Zalevsky, B. Meszaros, P. Bryant, L. L. Good, R. A. Laskowski, G. Pozzati, A. Shenoy, W. Zhu, P. Kundrotas, V. Ruiz-Serra, C. H. Rodrigues, , P. Beltrao

This study assesses AlphaFold 2's applications in structural biology, finding it outperforms existing tools in predicting disorder, complexes, and structural features with high confidence.

bioRxiv · Sep 26, 2021 · PreprintBiophysics

Transposable element landscape in Drosophila populations selected for longevity

D. K. Fabian, H. M. Donertas, M. Fuentealba Valenzuela, L. Partridge, J. M. Thornton

This study analyzes TE insertions and expression in long-lived Drosophila populations and finds increased TE abundance but reduced expression, suggesting improved telomere maintenance may contribute to longevity.

bioRxiv · Apr 23, 2020Evolutionary Biology

Drug repurposing for ageing research using model organisms

M. Ziehm, S. Kaur, D. K. Ivanov, P. J. Ballester, D. Marcus, L. Partridge, J. M. Thornton

This study ranks 743 drug-like compounds for their potential to modulate ageing in C. elegans and Drosophila using genetic, structural, and pharmacological data.

bioRxiv · Dec 22, 2016Pharmacology & Toxicology