Author

M.-C. Tsai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Research Focus:chromatin & epigenetic regulation· 3 Organism:human· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

B. ANTONNY· 2 shared D. DEBAYLE· 2 shared E. LEMICHEZ· 2 shared L. FLEURIOT· 2 shared A. Bertin· 1 shared A. METTOUCHI· 1 shared B. Mesmin· 1 shared C. MOREL· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

B. ANTONNY

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Author profile →

5 papers

Recent·Most cited

Exploiting De Novo Serine Synthesis as a Metabolic Vulnerability to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma

M. Teisseire, U. Sahu, J. Parola, M.-C. Tsai, V. Vial, J. Durivault, R. Grepin, Y. Cormerais, G. Pages, I. Ben-Sahra, S. Giuliano

This study identifies serine synthesis as a metabolic vulnerability in sunitinib-resistant renal cell carcinoma, showing that inhibiting key enzymes enhances drug sensitivity.

bioRxiv · Mar 22, 2024 · PreprintCancer Biology

Inducible lncRNA transgenic mice reveal continual role of HOTAIR in promoting breast cancer metastasis

Q. Ma, L. Yang, K. Tolentino, Y. Zhao, U. M. Lizenburger, Q. Shi, L. Zhu, M.-C. Tsai, J.-A. Chen, I. Lai, H. Zeng, L. Li, H. Chang

This study uses a transgenic mouse model to show that sustained HOTAIR expression promotes breast cancer metastasis and that its removal reverses metastatic traits, indicating an erasable epigenetic memory.

bioRxiv · Apr 21, 2022Cancer Biology

Docosahexaenoic fatty acid-containing phospholipids affect plasma membrane susceptibility to disruption by bacterial toxin-induced macroapertures

M.-C. TSAI, L. FLEURIOT, S. JANEL, D. GONZALEZ-RODRIGUEZ, C. MOREL, A. METTOUCHI, D. DEBAYLE, S. DALLONGEVILLE, J.-C. OLIVO-MARIN, B. ANTONNY, F. LAFONT, E. LEMICHEZ, H. BARELLI

The paper shows that DHA-containing phospholipids increase macroaperture formation in endothelial cells by reducing cell thickness, while maintaining overall transcellular area.

bioRxiv · Dec 23, 2020 · PreprintCell Biology

Molecular and cellular dissection of the OSBP cycle through a fluorescent inhibitor

T. Péresse, D. Kovacs, M. Subra, J. Bigay, M.-C. Tsai, J. Polidori, R. Gautier, S. Desrat, L. Fleuriot, D. Debayle, M. Litaudon, V. C. Pham, J. Bignon, B. Antonny, F. Roussi, B. Mesmin

The paper uses a fluorescent inhibitor to study OSBP lipid exchange and its effects on cellular processes.

bioRxiv · Nov 20, 2019 · PreprintCell Biology

Ezrin enrichment on curved membranes requires a specific conformation or interaction with a curvature-sensitive partner

F.-C. Tsai, A. Bertin, H. Bousquet, J. Manzi, Y. Senju, M.-C. Tsai, L. Picas, S. Miserey-Lenkei, P. Lappalainen, E. Lemichez, E. Coudrier, P. Bassereau

This study investigates how ezrin enrichment on curved membranes depends on its conformation or interaction with curvature-sensitive partners, showing that specific conformations and binding to I-BAR-domain proteins enable targeting to curved membranes.

bioRxiv · Apr 12, 2018Biophysics