Author

Mamoru Ishikawa

Japan Science and Technology Agency

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Hiroshi NonakaiD· 2 shared Itaru HamachiiD· 2 shared Seiji SakamotoiD· 2 shared Akihiro Tsushima· 1 shared Alexandru Radu AricescuiD· 1 shared Eriko MiuraiD· 1 shared Jae Hoon OhiD· 1 shared Kazuki Shiraiwa· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiochemistry

Hiroshi NonakaORCID

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2 papers

Recent·Most cited

In-brain construction of receptor-based protease sensors by coupling ligand-directed chemistry and click chemistry

Seiji Sakamoto, Kazuki Shiraiwa, Mengchu Wang, Mamoru Ishikawa, Hiroshi Nonaka, Itaru Hamachi

The paper develops a method to modify receptor proteins in the living mouse brain with fluorescent probes using ligand-directed and click chemistry, enabling high-resolution mapping of matrix metalloproteinase-9 activity near AMPARs.

Nature Synthesis · Jun 2, 2025Peer-reviewedBiochemistry

Revisiting PFA-mediated tissue fixation chemistry: FixEL enables trapping of small molecules in the brain to visualize their distribution dynamics

Hiroshi Nonaka, Takeharu Mino, Seiji Sakamoto, Jae Hoon Oh, Yu Watanabe, Mamoru Ishikawa, Akihiro Tsushima, Kazuma Amaike, Shigeki Kiyonaka, Tomonori Tamura, Alexandru Radu Aricescu, Wataru Kakegawa, Eriko Miura, Michisuke Yuzaki, Itaru Hamachi

The paper introduces FixEL, a method to trap and image small molecules in brain tissue, enabling visualization of their distribution and dynamics.

bioRxiv · Dec 21, 2021 · PreprintNeuroscience