Author

Manuel Klug

ETH Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

A MarinescuiD· 1 shared Carla HorváthiD· 1 shared Christelle Le FolliD· 1 shared Christian WolfrumiD· 1 shared Eshita KamaliD· 1 shared Fen Long· 1 shared Heike NeubaueriD· 1 shared Keila Navarro I BatistaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

A MarinescuORCID

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2 papers

Recent·Most cited

The nucleus accumbens shell regulates hedonic feeding via a rostral hotspot

A Marinescu, Eshita Kamal, Peter Leary, Keila Navarro I Batista, Manuel Klug, Nataša Savić, Christelle Le Foll, Marie A. Labouesse

This study identifies a rostral hotspot in the medial nucleus accumbens shell regulated by D1-SPNs that controls hedonic feeding, introducing Stard5 as a molecular marker for targeted manipulation.

eLife · Apr 27, 2026Peer-reviewedNeuroscience

Hepatic GCGR is required for the superior weight loss effects of a structurally related analogue of the dual GCGR/GLP1R agonist survodutide

Fen Long, Tenagne D. Challa, Vissarion Efthymiou, Manuel Klug, Thomas Klein, Heike Neubauer, Christian Wolfrum, Carla Horváth

The paper shows that hepatic GCGR is essential for the enhanced weight loss and lipid clearance effects of a dual GCGR/GLP1R agonist compared to a selective GLP1R agonist.

Diabetes Obesity and Metabolism · Dec 12, 2025Peer-reviewedPhysiology