Author

Laura Gasparini

AbbVie (Germany)ORCID 0000-0003-3894-9898Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Assay:bulk RNA-seq· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:protein structure prediction· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:C. elegans· 1

Frequent Co-Authors

Dagmar E. EhrnhoeferiD· 3 shared Annabelle SchlüteriD· 2 shared David C. SchöndorfiD· 2 shared Ebru Ercan-HerbstiD· 2 shared Janina S. Ried· 2 shared Peter ReinhardtiD· 2 shared Andreas Striebinger· 1 shared Aparna VasanthakumariD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

Dagmar E. EhrnhoeferORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

NeuroscienceFrontiers in Aging NeurosciencePeer-reviewedOct 26, 2026

New Insights on Bridging Integrator 1 Protein Isoforms as a Risk Increasing Gene in Alzheimer's Disease

Min Hu, Sahar Esmaeeli, Lindsay R. Stolzenburg…·Aparna Vasanthakumar

The paper identifies BIN1 isoform expression patterns and genetic variants associated with Alzheimer's disease risk using GWAS and hiPSC differentiation data.

DOI 10.3389/fnagi.2026.1937726

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologyAutophagyPeer-reviewedAug 25, 2025

A Novel C. elegans Model for Tau spreading Reveals Genes Critical for Endolysosomal Integrity and Seeded Tau Aggregation

Carl Alexander Sandhof, Nicole Martin, Jessica Tittelmeier…·Carmen I. Nussbaum-Krammer

12 citationstop 2%

C. elegansbulk RNA-seq

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NeuroscienceNeurobiology of AgingPeer-reviewedSep 17, 2021

Tau in the brain interstitial fluid is fragmented and seeding-competent

Erica Barini, Gudrun Plotzky, Yulia Mordashova…·Kerstin Schlegel

This study identifies fragmented, phosphorylated Tau in brain interstitial fluid from Tau transgenic mice and shows that only a subset of these fragments can seed Tau aggregation in vitro.

28 citations

mouseproteomics

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NeuroscienceMolecular NeurodegenerationPeer-reviewedJul 2, 2021

SETD7-mediated lysine monomethylation is abundant on non-hyperphosphorylated nuclear Tau

Maria Bichmann, Nuria Prat Oriol, Ebru Ercan-Herbst…·Dagmar E. Ehrnhoefer

The paper identifies lysine monomethylation on Tau by SETD7 in human brain tissue and shows its association with nuclear Tau in a mouse model of tauopathy.

31 citations

humanmouse

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