Author

Eriko Deguchi

Kyoto University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Kenta TeraiiD· 2 shared Michiyuki MatsudaiD· 2 shared Akira TanaveiD· 1 shared Alexander D. SorkiniD· 1 shared Beth L. PruittiD· 1 shared Daiki Hirayama· 1 shared Harmjan R. VosiD· 1 shared Joo Yong SimiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

Kenta TeraiORCID

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2 papers

Recent·Most cited

E-cadherin mechanotransduction activates EGFR-ERK signaling in epithelial cells by inducing ADAM-mediated ligand shedding

Ronja M. Houtekamer, Mirjam C. van der Net, Marjolein J. Vliem, Tomas E. J. C. Noordzij, Lisa van Uden, Robert M. van Es, Joo Yong Sim, Eriko Deguchi, Kenta Terai, Matthew A. Hopcroft, Harmjan R. Vos, Beth L. Pruitt, Michiyuki Matsuda, Willem‐Jan Pannekoek, Martijn Gloerich

This study shows mechanical strain activates EGFR-ERK signaling in epithelial cells via E-cadherin-induced ADAM17-mediated ligand shedding.

bioRxiv · Mar 6, 2025 · PreprintCell Biology

Low-affinity ligands of the epidermal growth factor receptor are long-range signal transmitters during collective cell migration of epithelial cells

Eriko Deguchi, Shuhao Lin, Daiki Hirayama, Kimiya Matsuda, Akira Tanave, Kenta Sumiyama, Shinya Tsukiji, Tetsuhisa Otani, Mikio Furuse, Alexander D. Sorkin, Michiyuki Matsuda, Kenta Terai

This study shows low-affinity EGFRLs like EREG and AREG transmit signals more efficiently than high-affinity ligands during collective cell migration and wound healing.

Cell Reports · Nov 1, 2024Peer-reviewedCell Biology