Comparative analysis of two autophagy-enhancing small molecules (AUTEN-67 and -99) in a Drosophila model of Spinocerebellar ataxia type 1
Tímea Burján, Maryam Aslam, Fanni Keresztes, Tímea Sigmond, Viktor Billes, Norbert Bencsik, Katalin Schlett, Tibor Vellai, Attila L. Kovács
This study evaluates two autophagy-enhancing compounds in a Drosophila SCA1 model, finding that only AUTEN-67 improves climbing and lifespan, with neuron-specific autophagy effects.
International Journal of Molecular Sciences · Oct 27, 2025Peer-reviewedCell Biology