Imipramine binds to amyloid-β and extends the survival of Alzheimer's disease patients
Noah R. Johnson, James Beham, Stefan Sillau, Juliana Read, Athena Ching-Jung Wang, Md. Mahiuddin Ahmed, Daphne Quang, Daniel Stephenson, Morkos Henen, Beat Vogeli, Heidi J. Chial, Robb Welty, Liliya Vugmeyster, Huntington Potter
This study shows imipramine binds to amyloid-β, reduces Aβ accumulation, and improves survival in Alzheimer's patients.
bioRxiv · Nov 3, 2026 · PreprintNeuroscience