Author

Melisa Merdanovic

University of Duisburg-Essen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Michael EhrmanniD· 2 shared Alessio LampisiD· 1 shared Alexa Rinsant· 1 shared Alexander CarpinteiroiD· 1 shared Amélie BonaudiD· 1 shared Anika BluemkeiD· 1 shared Arnaud JaccardiD· 1 shared Birte Hagemeier· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersPathology

Michael EhrmannORCID

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2 papers

Recent·Most cited

A mouse model of cardiac AL amyloidosis unveils mechanisms of tissue accumulation and toxicity of amyloid fibrils

Gemma Martinez-Rivas, Maria Victoria Ayala, Sébastien Bender, Gilles Roussine Codo, Karolina Weronika Świderska, Alessio Lampis, Laura Pedroza, Melisa Merdanovic, Pierre Sicard, Émilie Pinault, Laurence Richard, Francesca Lavatelli, Sofia Giorgetti, Diana Canetti, Alexa Rinsant, , Christophe Sirac

This paper develops a mouse model of cardiac AL amyloidosis that reproduces human disease features, including amyloid deposits and cardiac dysfunction, and identifies a role for partial LC degradation in fibril formation.

Nature Communications · Mar 27, 2025Peer-reviewedPathology

A non-autonomous protein quality control mechanism targeting tau aggregate propagation

Anika Bluemke, Birte Hagemeier, Kamilla Ripkens, Nina Schulze, Michal Strzala, Michelle Koci, Farnusch Kaschani, Markus Kaiser, Michael Erkelenz, Sebastian Schluecker, Melisa Merdanovic, Simon Poepsel, Doris Hellerschmied, Steven G. Burston, Michael Ehrmann

This study identifies HTRA1 as a non-autonomous protein quality control factor that inhibits tau aggregate propagation by interfering with multiple steps of the spreading process.

bioRxiv · Jul 26, 2024 · PreprintBiochemistry