Differential aberrant structural synaptic plasticity in axons and dendrites ahead of their degeneration in tauopathy
Johanna Jackson, James D. Johnson, S. Meftah, Tracey K. Murray, Zeshan Ahmed, Matteo Fasiolo, Michael L. Hutton, John T. R. Isaac, Michael J. O’Neill, Michael C. Ashby
This study tracks synapse plasticity in tauopathy and finds that changes in synaptic structure precede neurite degeneration, with distinct patterns in axons and dendrites.
bioRxiv · Apr 29, 2020 · PreprintNeuroscience