Author

Michelle A. Guney

University of Colorado Anschutz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Dylan SarbaughiD· 2 shared Lori SusseliD· 2 shared Bobbie‐Jo Webb‐RobertsoniD· 1 shared Cailin S. DeiteriD· 1 shared Carmella Evans‐MolinaiD· 1 shared Carrie NicoraiD· 1 shared Charles K. AnsongiD· 1 shared Christopher J. Hill· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersDevelopmental Biology

Dylan SarbaughORCID

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2 papers

Recent·Most cited

CHD4 and NKX2.2 Cooperate to Regulate Beta Cell Function by Repressing Non-Beta Cell Gene Programs

Dylan Sarbaugh, Thais Gaia Oliveira, Michelle A. Guney, McKenna R. Casey, Victoria M. Hoelscher, Christopher J. Hill, Cole R. Michel, Kristen L. Wells, Richard K.P. Benninger, Lori Sussel

This study identifies CHD4 as a cofactor of NKX2.2 that regulates beta cell function by repressing non-beta cell gene programs, leading to diabetes when disrupted.

bioRxiv · Jun 16, 2025 · PreprintDevelopmental Biology

The role of islet lipid composition remodeling in regulation of beta-cell death via ADP-ribosyl-acceptor glycohydrolase ARH3 signaling in insulitis

Ernesto Satoshi Nakayasu, Cailin S. Deiter, Jennifer E Kyle, Michelle A. Guney, Dylan Sarbaugh, Ruichuan Yin, Yi Cui, Carrie Nicora, Farooq Syed, Jonas Juan-Mateu, Raghavendra G. Mirmira, Carmella Evans‐Molina, Decio Laks Eizirik, Bobbie‐Jo Webb‐Robertson, Kristin Burnum-Johnson, , Charles K. Ansong

The paper investigates lipid composition changes in insulitis models and identifies ARH3 as a regulator of beta-cell apoptosis through PLA2G6 signaling.

bioRxiv · Mar 23, 2020 · PreprintSystems Biology