Combinatorial screening of biological degrader modules identifies heterobifunctional molecules that efficiently destroy MYC, leading to rapid tumour cell death in vitro and in vivo
Camilla Ascanelli, Samuel Gilberto, Christopher A. P. Batho, Gulesin Tunali, Min Ma, Matthew S. Glover, Adam Seaton, Jonathan D. Taylor, Hannah Richmond, Richard Butler, Sergio Martínez Cuesta, Sonja Hess, Walid T. Khaled, Ralph Minter, Heike Laman, , Catherine H. Wilson
bioRxiv · Jul 16, 2026 · PreprintBioengineering