Mohini R. Iyer

Identification of pre-existing microbiome and metabolic vulnerabilities to escalation of oxycodone self-administration and identification of a causal role of short-chain fatty acids in addiction-like behaviors.

The paper identifies microbiome and metabolic vulnerabilities linked to oxycodone self-administration escalation and shows SCFAs have a causal role in addiction-like behaviors.

Identification of individual differences in response to methadone, buprenorphine, and naltrexone in animal models of opioid use disorder

The paper tests individual differences in response to methadone, buprenorphine, and naltrexone in rats with opioid use disorder, finding varying efficacy based on addiction severity.