De novo design of phosphorylation-induced protein switches for synthetic signaling in cells
Stephen Buckley, Yangyang Miao, Mubarak Idris, Pao‐Wan Lee, Leo Scheller, Roland Riek, Sebastian J. Maerkl, Luciano A. Abriata, Bruno E. Correia
This paper designs phosphorylation-induced protein switches that control transcription in cells, demonstrating their functionality in synthetic signaling.
bioRxiv · Sep 10, 2025 · PreprintBioengineering